HEALTH PROFESSIONS IN ZAMORA IN THE MIDDLE OF THE EIGHTEENTH CENTURY


Early enzyme replacement therapy prevents dental and craniofacial abnormalities in a mouse model of mucopolysaccharidosis type VI

Mucopolysaccharidosis VI (MPS VI) is a hereditary lysosomal storage disease caused by the absence of the enzyme arylsulfatase B (ARSB).Craniofacial defects are common in MPS VI patients and manifest as abnormalities of the facial bones, teeth, and temporomandibular joints.Although enzyme replacement therapy (ERT) is the treatment of choice for MPS

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